Convenient, accurate, objective evaluation of Medication Adherence is a critical missing piece in achieving better control of cardiovascular disease (CVD) and its associated risk factors and complications.
Are your patients adhering to their cardiovascular (CV) medication prescription regimen?
It's hard to know, unless you use KardiAssure, the first and only adherence test for CV medications.
KardiAssure provides you with clear, reliable, actionable information on your patients' CV medication adherence, helping you provide the best possible care.
Cardiovascular Disease is the Leading Cause of Death in the U.S.
Hypertension affects 1 in 3 adults in the United States
Source: Merai R, Siegel C, Rakotz M, et al. CDC Grand Rounds: A Public Health Approach to Detect and Control Hypertension. MMWR Morb Mortal Wkly Rep. 2016 Nov 18;65(45):1261-1264.
Hypertension accounts for $46 billion in U.S. spend
Source: Mozzafarian D, Benjamin EJ, Go AS, et al. Heart Disease and Stroke Statistics-2015 Update: a report from the American Heart Association. Circulation. 2015;e29-322.
50% of hypertensive patients are non-adherent to their cardiovascular medications
Source: Abegaz MA, Shehab A, Gebreyohannes EA, et al. Nonadherence to antihypertensive drugs: A systematic review and meta-analysis. Medicine (Baltimore). 2017 Jan; 96(4): e5641.
125,000 preventable deaths per year related to nonadherence
Source: http://bemedicinesmart.org. National Council on Patient Information and Education. Accelerating Progress in Prescription Medicine Adherence: The Adherence Action Agenda. A National Action Plan to Address America’s “Other Drug Problem.” Updated: October 2013. Viewed: January 5, 2018.
Current Approaches Have Limitations
Directly observed drug administration
- Cumbersome and time-consuming, especially if daily visits to distant clinic are required
Physiologic or laboratory markers
- Cannot differentiate between lack of drug effect vs nonadherence
- Not available for all medications
Medication event monitoring systems (MEMS)
- Costly and many not be reimbursable
Patient self-reports accurately
- Limited by patient memory, ability to recall
- Low correlation with object measures
- Ability to be altered by patient
Pharmacy prescription refill data
- Difficult to obtain if multiple pharmacies used
- Does not ensure drug was ingested
- Over-the-counter medications such as aspirin not always reported
Introducing KardiAssure from Aegis Sciences Corporation
Aegis knows that it's more than just a test. KardiAssure provides insight at hand through the delivery of reliable and objective data that can help tailor treatment plans and improve outcomes. According to a 2017 study published in the journal Hypertension, urinalysis to determine nonadherence to prescribed antihypertensive medications is associated with improved adherence, contributing to subsequent improvements in blood pressure.
Direct analysis of biological fluids is called the most accurate method for evaluating adherence.
Capable of assessing 50+ relevant medications across 3 major CV conditions (hypertension, coronary artery disease, heart failure).
Non-invasive in-office collection and lab-based urinalysis – complete with integrated support team that simplifies performing test or interpreting results.
Product life-cycle support around-the-clock with a dedicated Sales, Client Services, and Clinical Scientist team.
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