Novel Psychoactive Substance Testing

Aegis is pleased to offer industry-leading testing options to allow providers the opportunity to more completely understand an individual’s substance use pattern, and facilitate more informed care.

Novel psychoactive substances (NPS) are compounds designed to mimic the effects of prescription drugs, evade detection by typical drug testing methodologies, and avoid regulation. NPS can be described by numerous terms, including legal highs or research chemicals labelled ‘not for human use’.

NPS markets rapidly change in response to regulation from US and other international agencies.
NPS may potentiate drug interactions with prescription medications, leading to unintended overdoses.
Individuals are exposed to fentanyl, designer opioids and benzodiazepines knowingly, or unknowingly through counterfeit prescription drugs intended to mimic common drugs such as oxycodone, hydrocodone and alprazolam, among others.

Ordering Information
Aegis' NPS testing is available for urine or oral fluid specimens as an add-on by drug class. Providers may choose one or multiple classes based on medical necessity.

Novel Psychoactive Substance Testing
The elements of our NPS test offerings are a testament to Aegis’ commitment to excellence and innovation. We continue to provide solutions that assist providers improve clinical care and prevent adverse outcomes. Current testing options include the following parent drugs and/or metabolites.

DESIGNER OPIOIDS	DESIGNER BENZODIAZEPINES	SYNTHETIC STIMULANTS	SYNTHETIC CANNABINOIDS
1-Napthyl U-47700	4Cl-Deschloroalprazolam	2-Fluoroamphetamine	4-CN-CUMYL-BUTINACA
2-Methyl AP-237	Adinazolam	2-Fluoromethamphetamine	4F-ABUTINACA
2-Napthyl U-47700	Bromazolam	2-Methoxymethamphetamine	4F-MDMB-BUTICA/4F-EMB-BUTICA
4-Trifluoromethyl U-47700	Clonazolam	3,4-DMMA	4F-MDMB-BUTINACA
Acryl Fentanyl	Desalkylgidazepam	3/4-Fluoroamphetamine	5F-AB-PFUPPYCA
AP-238	Deschloroetizolam	3/4-Fluoromethamphetamine	5F-AMB
Benzyl Fentanyl	Diclazepam	3/4-Methylmethcathinone	5F-BZO-POXIZID
Bromo Fentanyl	Etizolam	4F-3-methyl-alpha-PVP	5F-MDMB-PICA/5F-EMB-PICA
Brorphine	Flualprazolam	4-Fluoromethylphenidate	5F-MDMB-PINACA
Butonitazene	Flubromazepam	Alpha-D2PV	5F-PB-22
Chloro Fentanyl	Flubromazolam	Alpha-PHP	ADB-4en-PINACA
Cyclopropyl Fentanyl	Fluclotizolam	Alpha-PiHP	ADB-5Br-BUTINACA
Despropionyl Fluorofentanyl	Meclonazepam	Benzylone	ADB-5Br-INACA
Dipyanone	Metizolam	Butylone	ADB-5Br-PINACA
Flunitazene	Phenazepam	Chloro-N,N-DMC	ADB-BINACA
Fluoro Fentanyl		Dimethylone	ADB-BUTINACA
Fluoroisobutyryl Fentanyl	HALLUCINOGENS/DISSOCIATIVES	Eutylone	ADB-FUBIATA
Isotonitazene	25E-NBOH	MBZP	ADB-FUBICA
Methyl-THF-Fentanyl	2F-2-oxo-PCE	MDPHP	ADB-HEXINACA
Metonitazene	2F-Deschloroketamine	Methylenedioxy-PV8	ADB-PHETINACA
Norcarfentanil	3Cl-PCP	N,N-dimethyl Pentylone	ADB-PINACA
N-piperidinyl Etonitazene	3F-PCP	N-butyl Hexedrone	BZO-CHMOXIZID
N-pyrrolidino Etonitazene	3-OH-PCE	N-cyclohexyl Butylone	BZO-HEXOXIZID
N-pyrrolidino Metonitazene	3-OH-PCP	N-ethyl Heptedrone	BZO-POXIZID
N-pyrrolidino Protonitazene	Deschloroketamine	N-ethyl Hexedrone	CH-FUBIATA
Protonitazene	Deschloro-N-Ethylketamine	N-ethyl Pentedrone	CH-PIATA
Valeryl Fentanyl	Fluorexetamine	NM N-cyclohexyl Methylone	FUB-PB-22
	Hydroxetamine	N-propyl Butylone	JWH-018
OTHER	Methoxy PCE	Pentylone	JWH-073
Medetomidine	Methoxy PCP	TFMPP	MDMB-4en-PINACA
Phenibut			MDMB-5Br-INACA
Tianeptine			MMB-4en-PICA
Xylazine			MMB-4en-PINACA
			MMB-FUBICA

A complete and up to date list of the analytes contained in each listed drug class can be found at: www.aegislabs.com/Paincompthresholds

*Parent drug listed for informational purposes only and not included in testing. Analytes listed for each drug class are current as of September 11, 2023. Updates and enhancements to the drug classes are made from time to time.

Recorded Webinars Available:

If you are a Healthcare Provider seeking information please contact your Regional Sales Manager or Client Services team at 1.800.533.7052 or email Client.Services@aegislabs.com